Join us for next month’s webinar presenting research from University of California, Berkeley and Stanford University. The webinar features presentations and interactive discussions including recent findings and new developments in children’s environmental health.

The mission of the EPA/NIEHS Centers program is to reduce children’s health risks, protect children from environmental threats and promote their health and well-being in the communities where they live, learn and play.

1:00 p.m. - 1:20 p.m.:  History of CHAPS-SJV:  How We Came to Asthma, Immunology, Birth Outcomes with a Focus on PAHs
	Ira Tager Berkeley/Stanford Children's Environment Health Center

1:20 p.m. - 1:40 p.m.: A Bit of PAH Chemistry and How We Create Exposure Estimates

Katherine Hammond What you will learn: What are PAHs and what are their health effects? What are the temporal and spatial patterns of PAH concentrations in Fresno? How can we evaluate daily exposure to PAHs for 315 children over 8 years? Supporting Documents A spatial-temporal regression model to predict daily outdoor residential PAH concentrations in an epidemiologic study in Fresno, CA Noth, et al.

1:40 p.m. - 2:00 p.m.:  PAHs and Asthma--Relation to Phenotype; Relevance to Birth

Kari Nadeau What you will learn: Understand the importance of epigenetic studies in purified cell subsets in the immune system. To learn about new technologies (i.e. mass spectrometry-based immunophenotyping) to determine mechanisms of how toxicant exposure modulates immune cells. To be introduced to cell functional experiments that can link molecular events at the DNA level to clinical outcomes. Supporting Documents Ambient air pollution impairs regulatory T-cell function in asthma Nadeau, et al.

Biosketches

Katherine Hammond
Dr. Hammond is Professor and former Chair of Environmental Health Sciences at the University of California, Berkeley.  Her research has focused on assessment of exposure for environmental and occupational epidemiologic studies, including studies of the health effects of air pollution, diesel exhaust, secondhand smoke, semiconductor wafer production, and automobile manufacturing.  Occupational studies in progress include the Bay Area Solvent Study, which is examining the relationship between solvent exposure and neurologic and reproductive effects in automotive mechanics, and a study of cardiovascular effects of work in aluminum production.   A combination of her chemistry, industrial hygiene and epidemiology background enable her to develop innovative techniques to measure airborne contaminants and evaluate exposures.  Currently she heads the exposure assessment team for the Fresno Asthmatic Children’s Environment Study (FACES) and the Children’s Health and Air Pollution Study in the San Joaquin Valley (CHAPS- SJV).

Kari Nadeau
Dr. Kari Nadeau is Associate Professor of Pediatrics—Immunology and Allergy, and Associate Professor of Otolaryngology at Stanford University School of Medicine. She received her Bachelor of Science degree from Haverford College, an M.D. degree from Harvard Medical School and her Ph.D. from Harvard University in Biochemistry. The goal of the research in Dr. Nadeau's laboratory at Stanford is to investigate the role of ambient air exposure on the developing immune system in children, with a focus on understanding the interaction between environment and the immune system by studying detailed mechanistic studies in T cells. Dr. Nadeau has a broad background in immunology, with specific training and expertise in key research areas on T cells. She is working with Drs. Katharine Hammond and Ira Tager at the University of California, Berkeley, to link mechanistic immunology studies with epidemiological outcomes of ambient air pollution exposure. Dr. Nadeau has published more than 71 peer-reviewed papers, many of which focus on T cells and health outcomes.

Important Notice

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